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DeCS
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Descriptor English:
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Receptors, Notch
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Descriptor Spanish:
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Receptores Notch
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Descriptor Portuguese:
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Receptores Notch
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Synonyms English:
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Notch Receptors
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Tree Number:
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D12.776.543.750.725
D12.776.930.770
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Definition English:
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A family of conserved cell surface receptors that contain EPIDERMAL GROWTH FACTOR repeats in their extracellular domain and ANKYRIN repeats in their cytoplasmic domains. The cytoplasmic domain of notch receptors is released upon ligand binding and translocates to the CELL NUCLEUS where it acts as transcription factor. |
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History Note English:
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2006(1990)
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Allowable Qualifiers English:
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Record Number:
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51148
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Unique Identifier:
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D051880
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Occurrence in VHL:
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Similar:
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DeCS CID-10 SciELO LILACS LIS
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